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Infect Immun. 1974 August; 10(2): 293-298
Copyright © 1974 American Society for Microbiology. All Rights Reserved.

Serological Evidence for the Association of Bovine Respiratory Syncytial Virus with Respiratory Tract Disease in Alabama Cattle 1

C. R. Rossi and G. K. Kiesel

a Animal Health Research, Alabama Agricultural Experiment Station and School of Veterinary Medicine, Auburn University, Auburn, Alabama 36830

ABSTRACT

A serological investigation for neutralizing antibody to bovine respiratory syncytial virus (BRSV) was conducted using an antigenically related human strain of respiratory syncytial virus. Results demonstrated the effectiveness of the procedure. Sixty-seven percent of healthy, adult cattle tested were found to have antibody to BRSV. Calves in several herds were exposed to conditions to encourage development of respiratory tract disease. In three herds in which respiratory tract disease subsequently developed, the incidence of BRSV seroconversions approached 100%. In a herd in which no respiratory tract disease was detected, BRSV seroconversions indicated a high incidence of subclinical infections. It was concluded that, in this country as has been shown in others, BRSV is probably a significant pathogen of the bovine respiratory tract.


FOOTNOTES

1 Publication no. 1167. School of Veterinary Medicine, Auburn University, Auburn, Ala. 36830.


Infect Immun. 1974 August; 10(2): 293-298
Copyright © 1974 American Society for Microbiology. All Rights Reserved.