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Infect Immun. 1974 December; 10(6): 1307-1314
Copyright © 1974 American Society for Microbiology. All Rights Reserved.
1 Norden Laboratories, Lincoln, Nebraska 68521
Department of Veterinary Medicine, University of Bristol, Bristol, England
ABSTRACT
A total of 46 strains of feline calicivirus isolates from the United Kingdom, United States, Australia, and New Zealand were used in an investigation of their serological relationships based on the serum neutralization test. Although demonstrable antigenic variation exists between these isolates, it is shown that significant in vitro cross-activity exists between all these isolates to greater or lesser extent. All isolates tested may be regarded as serological variants of a single serotype of feline calicivirus. It is postulated that this relationship would provide for considerable cross-protection during successive exposures of cats to various feline caliciviruses.
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