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Infect Immun. 1975 February; 11(2): 290-293

Antiglobulin factors in normal mouse serum reacting with enzyme-digested gamma globulin.

J W Measel Jr and G C Cozad

ABSTRACT

The presence of antiglobulin factors in normal mouse serum was studied. Mice were injected with human 0 Rh(+) erythrocytes and the resulting gamma globulins were digested with papain. The reaction was demonstrated by agglutinations of human 0 Rh (+) perythryocytes sensitized with the Fab fragments when treated with normal mouse serum. Studies suggested that there are two factors in mice, a 7S AND A 19S globulin form. Cross-reactivity between strains of mice was demonstrated.

Infect Immun. 1975 February; 11(2): 290-293






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