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Infect Immun. 1975 June; 11(6): 1371-1374
Copyright © 1975 American Society for Microbiology. All Rights Reserved.

Systemic Amyloidosis in Mice Inoculated with Lyophilized Candida Cells

Stanley J. Mann and F. Blank

1 Skin and Cancer Hospital, Temple University Health Sciences Center, Philadelphia, Pennsylvania 19140

ABSTRACT

Injection of lyophilized Candida albicans or C. parapsilosis cells induced amyloidosis in outbred CFW mice. The disease process was irreversible, and a significant number of animals died of systemic amyloidosis within 400 days after the last treatment. The techniques described may represent a model system for the study of systemic amyloidosis.

Infect Immun. 1975 June; 11(6): 1371-1374
Copyright © 1975 American Society for Microbiology. All Rights Reserved.





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Copyright © 1975 by the American Society for Microbiology. All rights reserved.