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Infect Immun. 1975 June; 11(6): 1409-1412
Copyright © 1975 American Society for Microbiology. All Rights Reserved.

Effect of Temperature on Survival and Growth of Infectious Pancreatic Necrosis Virus ¹

Department of Biology, Utah State University, Logan, Utah 84322
Utah Division of Wildlife Resources, Fisheries Experiment Station, Logan, Utah 84321

ABSTRACT

Infectious pancreatic necrosis virus was stable for 10 days at 4 C in stream and well water, after which the virus had a half-life of 7.5 days. At 15 C, the virus was stable for 5 days, and then had a half-life between 5 and 6 days. Viral antigen in infected cells developed much more slowly at 4 C than at 20 C. Infected cells released infectious viral particles at temperatures as low as 4 C. Nutrition had a greater effect on the production of infectious virus at 4 C than at 20 C.

² Present address: Department of Pathology, School of Medicine, Wayne State University, Gordon H. Scott Hall, Detroit, Mich. 48201.

¹ Experiment Station journal paper no. 1941.