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Infect Immun. 1977 February; 15(2): 556-559

Killing of Escherichia coli by a granulocyte fraction occurs without recognizable ultrastructural alterations in the bacterial envelope, as studied by freeze-fracture electron microscopy.

A J Van Houte, P Elsbach, A Verkleij and J Weiss

ABSTRACT

Concentrations of a highly purified rabbit polymorphonuclear leukocyte fraction that rapidly caused irreversible loss of viability of Escherichia coli (S15) but reversible envelope alterations produced no recognizable morphological changes as studied by freeze-fracture electron microscopy. These findings support previous evidence that the killing of certain gram-negative microorganisms by granulocyte fractions occurs with minimal structural or functional disorganization of cytoplasmic and outer membranes.

Infect Immun. 1977 February; 15(2): 556-559






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