This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Moon, H W Articles by Orskov, I Search for Related Content PubMed PubMed Citation Articles by Moon, H W Articles by Orskov, I

 Previous Article  |  Next Article 

Infect Immun. 1977 February; 15(2): 614-620

Occurrence of K99 antigen on Escherichia coli isolated from pigs and colonization of pig ileum by K99+ enterotoxigenic E. coli from calves and pigs.

ABSTRACT

Several strains of enterotoxigenic Escherichia coli (ETEC) isolated from pigs were found to have an antigen (K99) previously reported only on strains of calf and lamb origin and which facilitates intestinal colonization in the latter two species. Several human ETEC were also tested for K99; however, none were positive. Each of four K99-positive ETEC strains of calf origin and one of pig origin produced K99 in pig ileum in vivo, adhered to villous epithelium in pig ileum, colonized pig ileum, and caused profuse diarrhea in newborn pigs. In contrast to the K99-positive strains above, four K99-negative ETEC from humans and chickens and one K99-positive ETEC from a calf either did not colonize pig ileum or did so inconsistently. When the K99-negative strains did colonize, they had little or no tendency to adhere to intestinal villi. These results are consistent with the hypothesis that K99 facilitates adhesion to and colonization of pig ileum by some ETEC.

This article has been cited by other articles:

• Do, T. N., Wilkie, I., Driesen, S. J., Fahy, V. A., Trott, D. J. (2006). Pathogenicity of Vietnamese Enterotoxigenic Escherichia coli Strains in Colostrum-deprived One-day-old Piglets.. Vet Pathol 43: 150-160 [Abstract] [Full Text]  
• Rahn, A., Beis, K., Naismith, J. H., Whitfield, C. (2003). A Novel Outer Membrane Protein, Wzi, Is Involved in Surface Assembly of the Escherichia coli K30 Group 1 Capsule. J. Bacteriol. 185: 5882-5890 [Abstract] [Full Text]  
• Tsolis, R. M. (2002). Comparative genome analysis of the alpha -proteobacteria: Relationships between plant and animal pathogens and host specificity. Proc. Natl. Acad. Sci. USA 99: 12503-12505 [Full Text]