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Infect Immun. 1977 March; 15(3): 846-849

Antitumor activity of a Brucella abortus preparation.

G Keleti, D S Feingold and J S Youngner

ABSTRACT

Mice injected intraperitoneally with sarcoma-180 cells develop ascites and eventually die. Intraperitoneal injection of a nonviable, aqueous... ether-extracted Brucella abortus preparation (BRU-PEL) as early as 7 days before or as late as 7 days after injection of tumor cells significantly inhibited development of ascites and protected against death. BRU-PEL was not effective if injected after ascites was grossly apparent. BRU-PEL was significantly more active than a Corynebacterium parvum preparation administered in the same way.

Infect Immun. 1977 March; 15(3): 846-849






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