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 Previous Article

Infect Immun. 1970 July; 2(1): 120-122
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Effect of Formalin Treatment on Electrophoretic Mobility of Cholera Toxin

Vito M. Esposito and John C. Feeley

1 Division of Biologics Standards, National Institutes of Health, Bethesda, Maryland 20014

ABSTRACT

Crude cholera toxin detoxified by treatment with Formalin showed an increased mobility and a decrease in the number of detectable protein constituents when compared with the parent toxin by disc electrophoresis. The significance of these observations in relation to the enhanced antigenic activity of cholera toxoid as compared to parent toxin is discussed.

Infect Immun. 1970 July; 2(1): 120-122
Copyright © 1970 American Society for Microbiology. All Rights Reserved.





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