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Infect Immun. 1979 August; 25(2): 569-573

Type C virus and immunoglobulin A production by murine myeloma MOPC-315: two independent activities.

A Gazit, A Yaniv, D Halperin and S Ben-Efraim

ABSTRACT

The suspected correlation between cessation of type C virus production and halt in immunoglobulin secretion by murine myeloma cells was studied. Employing two variants of the murine myeloma MOPC-315, immunoglobulin A-producing and nonproducing cells, we demonstrated that the two myelomas release similar levels of type C viruses which share common nucleotide sequences and that the viral genomes are equally expressed within the cells. Thus, the suggested relation between these two activities does not apply for MOPC-315 cells and probably for other murine myelomas also.

Infect Immun. 1979 August; 25(2): 569-573






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