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Infect Immun. 1979 October; 26(1): 232-234

Baculovirus replication in a mosquito (dipteran) cell line.

K E Sherman and A H McIntosh

ABSTRACT

The baculovirus from the lepidopteran host Autographa californica (alfalfa looper) was shown to replicate in a dipteran cell line without the production of characteristic polyhedral inclusion bodies. The low level of replication could not be detected by 50% tissue culture infective dose titrations, but was apparent by [3H]thymidine labeling of the viral genome. Immunoprecipitation of the radioactive product confirmed baculovirus production.

Infect Immun. 1979 October; 26(1): 232-234






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