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Infect Immun. 1971 February; 3(2): 274-277
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Partial Reassociation Between the Deoxyribonucleic Acids of Neisseria lactamicus and Neisseria meningitidis¹

^a Department of Microbiology, Naval Medical Research Institute, Bethesda, Maryland 20014

ABSTRACT

The similarity in polynucleotide sequence of seven strains of Neisseria lactamicus to N. meningitidis and to each other was investigated. The per cent reassociation between single-stranded N. lactamicus deoxyribonucleic acid (DNA), immobilized on membrane filters, with labeled single-stranded DNA fragments derived from strain SD-6 (group C) of N. meningitidis varied from 75 to 56. With strain ATCC 23972 of N. lactamicus furnishing the labeled DNA fragments, reassociation was 72% with N. meningitidis, 31% with N. subflava, and 98 to 72% with the other strains of N. lactamicus. It is concluded that on the basis of DNA reassociation N. lactamicus can be distinguished from N. meningitidis and N. subflava, but constitutes a relatively heterogeneous species.

² Permanent address: Institute of Virology, Slovak Academy of Sciences, Bratislava, Czechoslovakia.

¹ From the Bureau of Medicine and Surgery, Department of the Navy, Research Tasks MR005. 05.01-0008B and M4305. 01-1008.