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Infect Immun. 1971 March; 3(3): 411-415
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Effect of Antibiotic Treatment on the Incidence of Infectious Drug Resistance Among Intestinal Lactose-Fermenting Bacteria Isolated from Burn Patients

Alton B. Sturtevant Jr., Gail H. Cassell, Raymond A. Bobo and Thomas W. Feary

Departments of Microbiology, Comparative Medicine, and Clinical Pathology, The Medical Center, University of Alabama in Birmingham, Birmingham, Alabama 35233

ABSTRACT

Antibiotic-resistant lactose-fermenting bacteria were recovered from the feces of 20 of 25 burn patients studied. Of the Escherichia coli isolated from patients receiving antibiotic treatment, 81.5% were shown to be infectiously resistant; only 32% of the E. coli recovered from patients not receiving antibiotics were shown to be harboring R factors. Three resistance patterns, ampicillin-chloramphenicol-streptomycin-kanamycin, ampicillin-tetracycline, and ampicillin-streptomycin, accounted for 25.2, 20.3, and 15.4%, respectively, of the total R factors identified.

Infect Immun. 1971 March; 3(3): 411-415
Copyright © 1971 American Society for Microbiology. All Rights Reserved.





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