This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Wu, C.-H. Articles by Bergdoll, M. S. Search for Related Content PubMed PubMed Citation Articles by Wu, C.-H. Articles by Bergdoll, M. S.

Stimulation of Enterotoxin B Production I. Stimulation by Fractions from a Pancreatic Digest of Casein

Food Research Institute and Department of Bacteriology, University of Wisconsin, Madison, Wisconsin 53706

ABSTRACT

Chromatography on Dowex 50-X2 of Protein Hydrolysate Powder (Mead Johnson International, Evansville, Ind.), a pancreatic digest of casein, yielded 18 fractions. Five fractions stimulated enterotoxin production in greater amounts than were produced in the basal medium when it contained Protein Hydrolysate Powder. The stimulatory effect was due to the presence of peptides in the fractions. Many of these peptides contained large amounts of proline. Apparently, the primary structure of the peptides was important in the stimulation effect.