This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Csiza, C. K.
Right arrow Articles by Gillespie, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Csiza, C. K.
Right arrow Articles by Gillespie, J. H.

 Previous Article  |  Next Article 

Infect Immun. 1971 June; 3(6): 833-837
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Pathogenesis of Feline Panleukopenia Virus in Susceptible Newborn Kittens I. Clinical Signs, Hematology, Serology, and Virology 1

C. K. Csiza2, F. W. Scott, A. De Lahunta and J. H. Gillespie

a Departments of Microbiology and Anatomy, New York State Veterinary College, Cornell University, Ithaca, New York 14850

ABSTRACT

Inoculation of susceptible newborn kittens with a large dose of panleukopenia virus caused subclinical infection in 19 of 23 cases. All infected kittens developed severe and prolonged leukopenia. Cell-free virus was present in the blood from 1 to 7 postinoculation days. The virus spread to all organs, regardless of the route of inoculation. The thymus, spleen, mesenteric lymph nodes, and the cerebellum were the most severely infected organs. Kittens responded to virus infection by production of specific antibodies, first detectable in the circulatory system 6 to 8 days after infection. Antibody production preceded recovery from leukopenia by 3 days.

FOOTNOTES

2 Present address: Veterinary Science Laboratories, Division of Laboratories and Research, New York State Department of Health, Albany, N.Y. 12201.

1 Based upon a thesis presented by C. K. Csiza, to the faculty of the Graduate School of Cornell University in partial fulfillment of the requirements for the Ph.D. degree.

Infect Immun. 1971 June; 3(6): 833-837
Copyright © 1971 American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Meunier, P. C., Cooper, B. J., Appel, M. J. G., Lanieu, M. E., Slauson, D. O. (1985). Pathogenesis of Canine Parvovirus Enteritis: Sequential Virus Distribution and Passive Immunization Studies. Veterinary Pathology 22: 617-624 [Abstract]  


Copyright © 2010 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»