This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Crowle, P K Articles by Reed, N D Search for Related Content PubMed PubMed Citation Articles by Crowle, P K Articles by Reed, N D

 Previous Article  |  Next Article 

Infect Immun. 1981 July; 33(1): 54-58

Rejection of the intestinal parasite Nippostrongylus brasiliensis by mast cell-deficient W/Wv anemic mice.

ABSTRACT

The ability of W/Wv anemic mice to accumulate mucosal mast cells and to reject the intestinal parasite Nippostrongylus brasiliensis was examined. W/Wv mice did not accumulate mucosal mast cells in response to infections with N. brasiliensis. They eliminated a primary infection more slowly than did their normal littermate controls but were as refractory as controls to second and third infections. W/Wv mice had higher serum titers of worm-specific immunoglobulin E than did controls. These results indicate that mucosal mast cells are not an absolute requirement for N. brasiliensis rejection.

This article has been cited by other articles:

• Li, E., Zhao, A., Shea-Donohue, T., Singer, S. M. (2007). Mast Cell-Mediated Changes in Smooth Muscle Contractility during Mouse Giardiasis. Infect. Immun. 75: 4514-4518 [Abstract] [Full Text]  
• Gurish, M. F., Bryce, P. J., Tao, H., Kisselgof, A. B., Thornton, E. M., Miller, H. R., Friend, D. S., Oettgen, H. C. (2004). IgE Enhances Parasite Clearance and Regulates Mast Cell Responses in Mice Infected with Trichinella spiralis. J. Immunol. 172: 1139-1145 [Abstract] [Full Text]  
• McDermott, J. R., Bartram, R. E., Knight, P. A., Miller, H. R. P., Garrod, D. R., Grencis, R. K. (2003). Mast cells disrupt epithelial barrier function during enteric nematode infection. Proc. Natl. Acad. Sci. USA 100: 7761-7766 [Abstract] [Full Text]  
• Vallance, B. A., Blennerhassett, P. A., Huizinga, J. D., Collins, S. M. (2001). Mast cell-independent impairment of host defense and muscle contraction in T. spiralis-infected W/WV mice. Am. J. Physiol. Gastrointest. Liver Physiol. 280: G640-G648 [Abstract] [Full Text]  
• Friend, D. S., Gurish, M. F., Austen, K. F., Hunt, J., Stevens, R. L. (2000). Senescent Jejunal Mast Cells and Eosinophils in the Mouse Preferentially Translocate to the Spleen and Draining Lymph Node, Respectively, During the Recovery Phase of Helminth Infection. J. Immunol. 165: 344-352 [Abstract] [Full Text]  
• Miller, H. R.P., Wright, S. H., Knight, P. A., Thornton, E. M. (1999). A Novel Function for Transforming Growth Factor-{beta}1: Upregulation of the Expression and the IgE-Independent Extracellular Release of a Mucosal Mast Cell Granule-Specific {beta}-Chymase, Mouse Mast Cell Protease-1. Blood 93: 3473-3486 [Abstract] [Full Text]