This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Minah, G E Articles by Finney, J P Search for Related Content PubMed PubMed Citation Articles by Minah, G E Articles by Finney, J P

 Previous Article  |  Next Article 

Infect Immun. 1981 December; 34(3): 662-675

Sucrose-induced ecological response of experimental dental plaques from caries-free and caries-susceptible Human volunteers.

G E Minah, G B Lovekin and J P Finney

ABSTRACT

Microbial succession, experimental cariogenicity, and sucrose metabolism were examined in dental plaques which developed on sterile bovine enamel inserts in acrylic palatal appliances. The appliances were worn for a period of 14 days by 10 caries-free and 10 caries-susceptible human volunteers. Three of six enamel inserts on each appliance were exposed extraorally to 10% sucrose in 0.85% saline six times a day, and three were exposed simultaneously to 0.85% saline as a control environment. The responses of the plaques to the high-sucrose environment in both caries status populations were compared. In all plaques, exposure to 10% sucrose stimulated the succession of Veillonella spp., Lactobacillus spp., Streptococcus salivarius, and, to a lesser extent, Streptococcus mutans and a decline in levels of Streptococcus sanguis, Neisseria spp., and gram-negative anaerobic rods. Plaques from caries-free mouths, in contrast to those from caries-susceptible mouths, harbored higher levels of Veillonella spp., gram-negative anaerobic rods, and Neisseria spp. and lower levels of Lactobacillus spp. Sucrose-exposed plaques from caries-free mouths also induced less enamel microhardness changes and formed less lactic acid from [14C]sucrose during a 60-min incubation at 37 degrees C than did comparable plaques from caries-susceptible mouths. The experiments revealed consistent differences in the ecological response to a cariogenic substrate environment in plaques from the two populations, with plaques from caries-free subjects exhibiting less cariogenic potential than those from caries-susceptible subjects.

---

Infect Immun. 1981 December; 34(3): 662-675

This article has been cited by other articles:

• Leme, A.F. P., Koo, H., Bellato, C.M., Bedi, G., Cury, J.A. (2006). The Role of Sucrose in Cariogenic Dental Biofilm Formation--New Insight. JDR 85: 878-887 [Abstract] [Full Text]  
• Touger-Decker, R., van Loveren, C. (2003). Sugars and dental caries. Am. J. Clin. Nutr. 78: 881S-892 [Abstract] [Full Text]  
• Pratten, J., Bedi, R., Wilson, M. (2000). An In Vitro Study of the Effect of Fluoridated Milk on Oral Bacterial Biofilms. Appl. Environ. Microbiol. 66: 1720-1723 [Abstract] [Full Text]  
• Lingstrom, P., Van Ruyven, F.O.J., Van Houte, J., Kent, R. (2000). The pH of Dental Plaque in its Relation to Early Enamel Caries and Dental Plaque Flora in Humans. JDR 79: 770-777 [Abstract]  
• Bowden, G.H.W., Li, Y.H. (1997). Nutritional Influences on Biofilm Development. ADR 11: 81-99 [Abstract]  
• van Houte, J., Lopman, J., Kent, R. (1994). The Predominant Cultivable Flora of Sound and Carious Human Root Surfaces. JDR 73: 1727-1734 [Abstract]  
• Fejerskov, O., Nyvad, B., Larsen, M. J. (1994). Human Experimental Caries Models: Intra-Oral Environmental Variability. ADR 8: 134-143 [Abstract]  
• Van Houte, J., Sansone, C., Joshipura, K., Kent, R. (1991). In vitro Acidogenic Potential and Mutans Streptococci of Human Smooth-surface Plaque Associated with Initial Caries Lesions and Sound Enamel. JDR 70: 1497-1502 [Abstract]  
• De Jong, M.H., Van den Kieboom, C.W.A., Lukassen, J.A.M., Van der Hoeven, J.S. (1985). Effects of Dietary Carbohydrates on the Numbers of Streptococcus mutans and Actinomyces viscosus in Dental Plaque of Mono-infected Gnotobiotic Rats. JDR 64: 1134-1137 [Abstract]