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Infect Immun. 1971 October; 4(4): 488-491
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Inhibition of Pseudomonas aeruginosa by Hyperbaric Oxygen II. Ultrastructural Changes

¹ Department of Microbiology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107
Department of Microbiology, Temple University School of Dentistry, Philadelphia, Pennsylvania 19140

ABSTRACT

The ultrastructure of Pseudomonas aeruginosa cells treated with hyperbaric oxygen for 20 to 24 hr was examined by electron microscopy. A marked difference in the morphology of the nuclear area and cytoplasm of experimental cells was noted when compared to control cells grown under normobaric conditions. This difference was characterized by the absence of a definitive nuclear area and a reduced granularity of the cytoplasm.