IAI FigSearch
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Leijh, P C
Right arrow Articles by van Furth, R
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Leijh, P C
Right arrow Articles by van Furth, R

 Previous Article  |  Next Article 

Infect Immun. 1984 November; 46(2): 448-452

Effect of thioglycolate on phagocytic and microbicidal activities of peritoneal macrophages.

P C Leijh, T L van Zwet, M N ter Kuile and R van Furth

ABSTRACT

Brewer thioglycolate-elicited mouse peritoneal macrophages were as active as resident peritoneal macrophages in the phagocytosis of opsonized Staphylococcus epidermidis but were unable to kill ingested microorganisms. This decreased functional activity was restricted to Brewer thioglycolate-elicited macrophages, since peritoneal macrophages elicited with NIH thioglycolate, alone or supplemented with agar and methylene blue, were as active as resident peritoneal macrophages. No effect of agar on the functional activities of macrophages was observed. A defective intracellular killing by peritoneal macrophages due to Brewer thioglycolate was seen only after an intraperitoneal injection with thioglycolate, not after in vitro incubation of resident macrophages with thioglycolate. The results of this study show that, depending on the kind of thioglycolate used, the functional characteristics of elicited macrophages may alter. However, none of the forms of thioglycolate investigated induced the recruitment of activated macrophages.


Infect Immun. 1984 November; 46(2): 448-452




This article has been cited by other articles:




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
J. Bacteriol. J. Virol. Eukaryot. Cell
Microbiol. Mol. Biol. Rev. Clin. Vaccine Immunol. All ASM Journals

Copyright © 1984 by the American Society for Microbiology. All rights reserved.