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Infect Immun. 1972 January; 5(1): 31-34
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Experimental Oral Immunization with L-Forms of Vibrio cholerae

^a Department of Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

ABSTRACT

It has been found that oral administration of lysates of L-forms of Vibrio cholerae are antigenic and capable of eliciting an early and high coproantibody response. The L-forms of V. cholerae did not produce any booster effect. Coproantibody rise persists to significant levels even six weeks after oral immunization. L-form lysates of V. cholerae also produce a considerable rise of circulating antibodies and these persist in significantly high titers up to six weeks.

¹ Present address: Professor of Microbiology, Jawaharlal Institute of Postgraduate Medical Education & Research, Pondicherry-6, India.