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Infect Immun. 1972 April; 5(4): 570-582
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Electron Microscopy Observations on a New Herpes-Type Virus Isolated from Iguana iguana and Propagated in Reptilian Cells In Vitro

^a Viral Oncology Department, Roswell Park Memorial Institute, and Departments of Pediatrics and Microbiology, School of Medicine, State University of New York, Buffalo, New York 14203

ABSTRACT

Ultrastructural observations on a new viral isolate, designated iguana virus, indicate that it is consistently present in intranuclear inclusions, possesses a ± 115-nm nucleocapsid, ranges from 165 to 300 nm in diameter in the enveloped form, and exhibits cubic symmetry (probably 162 capsomeres). It is concluded that it is a herpes-type virus, the morphological evidence being in agreement with and supporting the biological and physical characteristics presented by Clark and Karzon. Several fine-structural features, among them the encapsidization of small 35-nm hexagonal bodies and the viral membrane envelope enclosure of cell-derived moieties are presented and discussed.

¹ Wistar Institute, Philadelphia, Pa. 19104.