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Infect Immun. 1985 December; 50(3): 807-812

Local transfer of delayed-type hypersensitivity after Salmonella infection in mice.

S R Attridge and I Kotlarski

ABSTRACT

An adoptive local transfer system has been used to study the mediators of delayed-type hypersensitivity induced in mice by infection with Salmonella enteritidis 11RX. The cells which transfer this state of hypersensitivity to untreated recipients are nonadherent T lymphocytes with the surface phenotype Lyt 1+2-, and successful transfer requires compatibility at the I-A subregion of the H-2 complex. In these and other respects these cells are indistinguishable from those previously found to be responsible for in vitro lymphokine release upon culture with 11RX antigens.


Infect Immun. 1985 December; 50(3): 807-812




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