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Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies.

ABSTRACT

Mice injected with either of two monoclonal antibodies specific for the O polysaccharide of Brucella abortus prior to challenge infection had viable counts in spleens and livers significantly below those in control groups 1 and 4 weeks later. Two monoclonal antibodies specific for the porin of B. abortus failed to confer protection.

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