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Infect Immun. 1986 October; 54(1): 28-31

Polyclonal response of human lymphocytes to Chlamydia trachomatis.

L Räsänen, M Lehtinen, M Lehto, J Paavonen and P Leinikki

ABSTRACT

The mitogenicity of Chlamydia trachomatis was investigated. Umbilical cord blood cells from healthy newborns were used. These cells were stimulated in cultures with partially purified C. trachomatis elementary bodies. Proliferation of cultured lymphocytes and secreted immunoglobulins and leukocyte migration inhibitory factor were measured in the culture supernatants. Our results showed that C. trachomatis is able to elicit polyclonal antibody, lymphokine, and DNA synthesis.

Infect Immun. 1986 October; 54(1): 28-31




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