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Infect Immun. 1988 November; 56(11): 3001-3003

A pneumococcal surface protein (PspB) that exhibits the same protease sensitivity as streptococcal R antigen.

Department of Microbiology, University of Alabama, Birmingham 35294.

ABSTRACT

A monoclonal antibody against Streptococcus pneumoniae, designated T4A49, detected a 64,000-molecular-weight protein that was immunologically unrelated to the previously described surface protein PspA. This new protein, designated PspB, was pepsin sensitive and trypsin resistant, as is the R antigen of type 28 group A streptococci.

This article has been cited by other articles:

• Briles, D. E., Tart, R. C., Swiatlo, E., Dillard, J. P., Smith, P., Benton, K. A., Ralph, B. A., Brooks-Walter, A., Crain, M. J., Hollingshead, S. K., McDaniel, L. S. (1998). Pneumococcal Diversity: Considerations for New Vaccine Strategies with Emphasis on Pneumococcal Surface Protein A (PspA). Clin. Microbiol. Rev. 11: 645-657 [Abstract] [Full Text]