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Infect Immun. 1988 February; 56(2): 529-531

Haemophilus influenzae serotype a: outer membrane protein classification and correlation with DNA polymorphism at the cap locus.

I Allan, J S Kroll, A Dhir and E R Moxon

Department of Paediatrics, John Radcliffe Hospital, Headington, Oxford, United Kingdom.

ABSTRACT

Fifty-four temporally and geographically distinct isolates of Haemophilus influenzae serotype a were characterized by (i) outer membrane protein composition and (ii) DNA polymorphism at the cap locus. In 53 of 54 cases, knowledge of the outer membrane protein type was accurately predictive of the cap locus polymorphism, suggesting that the majority of H. influenzae (type a) isolates have evolved from a limited number of clones.

Infect Immun. 1988 February; 56(2): 529-531






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