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Infect Immun. 1989 January; 57(1): 235-238

Effect of oral immunization with Pseudomonas aeruginosa on the development of specific antibacterial immunity in the lungs.

J Freihorst, J M Merrick and P L Ogra

Department of Pediatrics, Children's Hospital, Buffalo, New York 14222.

ABSTRACT

Oral administration of Pseudomonas aeruginosa to rats elicited a systemic and mucosal antibody response in the intestinal and respiratory tracts. The antibody response did not influence the course of the disease when immunized animals were subsequently challenged by the introduction of viable bacteria into the lungs.

Infect Immun. 1989 January; 57(1): 235-238




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Copyright © 1989 by the American Society for Microbiology. All rights reserved.