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Infect Immun. 1989 August; 57(8): 2470-2474

A major antigen on the outer envelope of a human oral spirochete, Treponema denticola.

T Umemoto, I Namikawa, H Suido and S Asai

Department of Oral Microbiology, School of Dentistry, Asahi University, Gifu, Japan.

ABSTRACT

Human oral spirochetes are prominent inhabitants of subgingival plaque in patients with periodontal disease. By immunoelectron microscopy using protein A-gold complexes and either polyclonal mouse antiserum against the 53-kDa antigen or 53-kDa-antigen-specific monoclonal antibody, a major polypeptide antigen, with a molecular weight of 53,000 (molecular size, 53 kilodaltons [kDa]), of a human oral spirochete, Treponema denticola ATCC 33520, was found to localize on the surface of the outer envelope.

Infect Immun. 1989 August; 57(8): 2470-2474




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