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Infect Immun. 1990 March; 58(3): 833-834

Murine gamma interferon fails to inhibit Toxoplasma gondii growth in murine fibroblasts.

J D Schwartzman, S L Gonias and E R Pfefferkorn

Department of Pathology, University of Virginia School of Medicine, Charlottesville 22908.

ABSTRACT

Although treatment of human macrophages or fibroblasts with human gamma interferon results in the inhibition of intracellular Toxoplasma gondii, murine gamma interferon stimulated only murine macrophages, not murine fibroblasts, to inhibit T. gondii. This species difference may be important in understanding the control of acute and chronic toxoplasmosis.

Infect Immun. 1990 March; 58(3): 833-834




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