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Infect Immun. 1972 July; 6(1): 32-37
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Immunochemistry of the Capsular Polysaccharides from Clostridium perfringens: Selected Hobbs Strains 1, 5, 9, and 10 ¹

^a Departments of Chemistry and Biology, Georgia State University, Atlanta, Georgia 30303

ABSTRACT

The properties of the immunochemically distinct substances isolated from four strains of Clostridium perfringens, mucoid variants of Hobbs 1, 5, 9, and 10, were shown to be compatible with the hypothesis that polysaccharides are generally responsible for the "type-specificity" of these organisms. The presence of "group-specific" substance was demonstrated by the cross-reaction of recent preparations of Hobbs 5 antisera with the isolated polysaccharides. The cross-reactions were not observed with specific antisera of the other strains studied and were independent of the "type-specific" phenomenon.

¹ The material presented is taken in part from a thesis submitted by B. G. Henderson to the graduate School of Arts and Sciences of Georgia State University in partial fulfillment of the requirements for the M.S. degree.