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Demonstration of Antigenic Identity Between Purified Equine Infectious Anemia Virus and an Antigen Extracted from Infected Horse Spleen

Equine Infectious Anemia Research Division, National Institute of Animal Health, Kodaira, Tokyo, 187 Japan
New York State Veterinary College, Cornell University, Ithaca, New York 14850

ABSTRACT

Antigenic relationship between purified equine infectious anemia (EIA) virus and spleen-derived antigen from EIA-infected horses was examined by immunodiffusion. Identical antigenicity of these two antigens has been proven because precipitation lines formed between the two antigens and EIA antiserum connected with each other. The results indicate that the antigenic substance derived from infected spleen is a component of EIA virus.