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Infect Immun. 1972 December; 6(6): 909-912
Copyright © 1972 American Society for Microbiology. All Rights Reserved.
Department of Microbiology, Alexander Stone Building, University of Glasgow Garscube Estate, Bearsden, Glasgow, Scotland
ABSTRACT
Mycobacterium leprae organisms isolated from infected spleen and liver tissue by zonal centrifugation were shown to possess adjuvant activity. Histochemical examination of the footpad macrophage epithelioid granuloma showed that macrophages contained large amounts of hemosiderin after the injection of M. leprae and much smaller amounts after the injection of M. tuberculosis.
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