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Infect Immun. 1993 December; 61(12): 5410-5412

Class II major histocompatibility complex molecule expression on murine eosinophils activated in vivo by Brugia malayi.

S D Mawhorter, E Pearlman, J W Kazura and W H Boom

Division of Geographic Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106-4984.

ABSTRACT

The Th-2 response to microfilariae of Brugia malayi in BALB/c mice is associated with peritoneal eosinophilia. These eosinophils had an activated hypodense phenotype in vivo and expressed high levels of the class II major histocompatibility complex (MHC). Interleukin 4 up-regulated the class II MHC, whereas gamma interferon inhibited class II MHC expression on eosinophils.


Infect Immun. 1993 December; 61(12): 5410-5412




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