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Infect Immun. 1993 July; 61(7): 3081-3083

Antimicrobial activity of two bactenecins against spirochetes.

M Scocchi, D Romeo and M Cinco

Department of Biochemistry, Biophysics and Macromolecular Biochemistry, University of Trieste, Italy.

ABSTRACT

Bac5 and Bac7 are antimicrobial peptides of bovine neutrophils that act on enteric gram-negative bacteria. We report here that these two peptides immobilize and kill Leptospira interrogans and Leptospira biflexa with MBCs of 6 to 25 micrograms/ml. Conversely, although both peptides bind to Borrelia burgdorferi, the organism is resistant to their action.

Infect Immun. 1993 July; 61(7): 3081-3083




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