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Infection and Immunity, July 1994, p. 2991-2994, Vol. 62, No. 7
0019-9567/1994/$04.00+0     DOI:

research-article

Ferritin stimulation of a monokine inhibitor of lipopolysaccharide-augmented myelopoiesis is ferroxidase dependent.

R Kreisberg, H E Broxmeyer, and R N Moore

Department of Microbiology, University of Tennessee, Knoxville 37996-0845.

ABSTRACT

Ferritin inhibition of myelopoiesis has been associated with intrinsic ferroxidase activity of heavy-chain ferritin and with production of a monokine inhibitor of lipopolysaccharide (LPS)-augmented monocytopoiesis. We report here that intrinsic ferroxidase activity of heavy-chain ferritin is required for stimulated production of the monokine inhibitor of LPS-augmented monocytopoiesis.

Infection and Immunity, July 1994, p. 2991-2994, Vol. 62, No. 7
0019-9567/1994/$04.00+0     DOI:






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