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Infect. Immun., 01 1998, 353-355, Vol 66, No. 1
Copyright © 1998, American Society for Microbiology

A new gene family (ariel) encodes asparagine-rich Entamoeba histolytica antigens, which resemble the amebic vaccine candidate serine-rich E. histolytica protein

Z Mai and J Samuelson
Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts 02125, USA.

A family of genes, called ariel, are named for and encode asparagine- rich Entamoeba histolytica antigens containing 2 to 16 octapeptide repeats. Ariel proteins, which are constitutively expressed by trophozoites, belong to a large antigen family that includes the serine- rich E. histolytica protein (SREHP), an amebic vaccine candidate.


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