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Infection and Immunity, November 1999, p. 6213-6216, Vol. 67, No. 11
0019-9567/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

P48 Major Surface Antigen of Mycoplasma agalactiae Is Homologous to a malp Product of Mycoplasma fermentans and Belongs to a Selected Family of Bacterial Lipoproteins

Sergio Rosati,1 Sarah Pozzi,2 Patrizia Robino,1 Barbara Montinaro,3 Amedeo Conti,4 Manlio Fadda,3 and Marco Pittau3,*

Dipartimento di Produzioni Animali, Epidemiologia ed Ecologia, Università degli Studi di Torino, Torino,1 Laboratorio di Immunogenetica, Istituto Nazionale dei Tumori, Centro di Biotecnologie Avanzate, Genova,2 Istituto di Patologia Speciale e Clinica Medica Veterinaria, Università degli Studi di Sassari, Sassari,3 and Centro Studio Alimentazione Animali, CNR, Torino,4 Italy

Received 17 May 1999/Returned for modification 23 June 1999/Accepted 9 August 1999

A major surface antigenic lipoprotein of Mycoplasma agalactiae, promptly recognized by the host's immune system, was characterized. The mature product, P48, showed significant similarity and shared conserved amino acid motifs with lipoproteins or predicted lipoproteins from Mycoplasma fermentans, Mycoplasma hyorhinis, relapsing fever Borrelia spp., Bacillus subtilis, and Treponema pallidum.

* Corresponding author. Mailing address: Istituto di Patologia Speciale e Clinica Medica Veterinaria, Università degli Studi di Sassari, Facoltà di Medicina Veterinaria, Via Vienna 2, 07100 Sassari, Italy. Phone: 39 079 229449. Fax: 39 079 229451. E-mail: pittau{at}ssmain.uniss.it.

Infection and Immunity, November 1999, p. 6213-6216, Vol. 67, No. 11
0019-9567/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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Copyright © 1999 by the American Society for Microbiology. All rights reserved.