Infection and Immunity, June 1999, p. 3146-3150, Vol. 67, No. 6
0019-9567/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
Department of Microbiology and Immunology, University of Kentucky College of Medicine, Lexington, Kentucky, 40536-0084,1 and Department of Veterinary Science, University of Kentucky, Lexington, Kentucky 40536-00762
Received 15 December 1998/Returned for modification 26 February 1999/Accepted 4 March 1999
Borrelia burgdorferi can persistently infect mammals despite their production of antibodies directed against bacterial proteins, including the Erp lipoproteins. We sequenced erp loci of bacteria reisolated from laboratory mice after 1 year of infection and found them to be identical to those of the inoculant bacteria. We conclude that recombination of erp genes is not essential for chronic mammalian infection.
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