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Infection and Immunity, December 2000, p. 7186-7189, Vol. 68, No. 12
0019-9567/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Disease Outcome Subsequent to Primary and Secondary Urogenital Infection with Murine or Human Biovars of Chlamydia trachomatis

Kyle H. Ramsey,* Jennifer L. DeWolfe, and Rena D. Salyer

Microbiology Department, Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois 60515

Received 26 June 2000/Returned for modification 18 September 2000/Accepted 25 September 2000

A susceptible strain of mice infected intravaginally with the mouse pneumonitis biovar of Chlamydia trachomatis became infertile and sustained high rates of hydrosalpinx formation regardless of prior infection with a human serovar. Conversely, susceptible mice infected with human serovars remained fertile unless challenged with a homologous human serovar.

* Corresponding author. Mailing address: Microbiology Department, Chicago College of Osteopathic Medicine, Midwestern University, 555 31st St., Downers Grove, IL 60515. Phone: (630) 515-6165. Fax: (630) 515-7245. E-mail: kramse{at}midwestern.edu.

Infection and Immunity, December 2000, p. 7186-7189, Vol. 68, No. 12
0019-9567/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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