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Infection and Immunity, August 2000, p. 4805-4810, Vol. 68, No. 8
0019-9567/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Antigen Specificity of T-Cell Response to Mycobacterium avium Infection in Mice

Teresa F. Pais, Joana Feijó Cunha, and Rui Appelberg*

Laboratory of Microbiology and Immunology of Infection, Institute for Molecular and Cell Biology, University of Porto, Porto, Portugal

Received 29 February 2000/Returned for modification 31 March 2000/Accepted 5 May 2000

T cells from Mycobacterium avium-infected C57BL/6 mice reacted to culture filtrate, envelope, and cytosol proteins and to fractions obtained from these proteins. Multiple targets were recognized, such as 29- to 45-kDa and <21-kDa antigens of the culture filtrate, antigens of around 30 kDa in the envelope and cytosol, and 45- to 116-kDa proteins in the envelope.

* Corresponding author. Mailing address: Laboratory of Microbiology and Immunology of Infection, Institute for Molecular and Cell Biology, University of Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal. Phone: 351.226074952. Fax: 351.226099157. E-mail: rappelb{at}ibmc.up.pt.

Infection and Immunity, August 2000, p. 4805-4810, Vol. 68, No. 8
0019-9567/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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