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Infection and Immunity, February 2001, p. 627-639, Vol. 69, No. 2
0019-9567/01/$04.00+0   DOI: 10.1128/IAI.69.2.627-639.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

MINIREVIEW

Genetics of Surface Antigen Expression in Pneumocystis carinii

James R. Stringer* and Scott P. Keely

Department of Molecular Genetics, Biochemistry, and Microbiology, College of Medicine, University of Cincinnati, Cincinnati, Ohio 45267

This article reviews the molecular genetic data pertaining to the major surface glycoprotein (MSG) gene family of Pneumocystis carinii and its role in surface variation and compares this fungal system to antigenic variation systems in the protozoan Trypanosoma brucei and the bacteria Borrelia spp.


* Corresponding author. Mailing address: Department of Molecular Genetics, Biochemistry, and Microbiology, College of Medicine, Mail Location 524, University of Cincinnati, Cincinnati, OH 45267-0524. Phone: (513) 558-0069. Fax: (513) 558-8474. E-mail: stringjr{at}ucmail.uc.edu.


Infection and Immunity, February 2001, p. 627-639, Vol. 69, No. 2
0019-9567/01/$04.00+0   DOI: 10.1128/IAI.69.2.627-639.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.



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