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Infection and Immunity, March 2001, p. 1876-1879, Vol. 69, No. 3
0019-9567/01/$04.00+0 DOI: 10.1128/IAI.69.3.1876-1879.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
Experimental Model of Human Body Louse Infection
Using Green Fluorescent Protein-Expressing Bartonella
quintana
Pierre-Edouard
Fournier,1
Michael F.
Minnick,2
Hubert
Lepidi,1,3
Eric
Salvo,1 and
Didier
Raoult1,*
Unité des rickettsies, CNRS:UPRESA
6020,1 and Laboratoire
d'Histologie,3 Faculté de
Médecine, Université de la Méditerranée,
13385 Marseille Cedex 05, France, and Division of
Biological Sciences, University of Montana, Missoula, Montana
59812-10022
Received 7 August 2000/Accepted 18 October 2000
A laboratory colony of human body lice was experimentally infected
by feeding on rabbits made artificially bacteremic with a green
fluorescent protein-expressing Bartonella quintana. B. quintana was detected in the gut and feces until death but not in
the eggs. The life span of the lice was not modified. The rabbit model
should provide valuable clues to the role of lice in the transmission
of B. quintana.
*
Corresponding author. Mailing address: Unité des
Rickettsies, CNRS:UPRESA 6020, Faculté de Médecine,
Université de la Méditerranée, 27 Blvd Jean Moulin,
13385 Marseille Cedex 05, France. Phone: (33) 04-91-38-55-17. Fax: (33)
04-91-83-03-90. E-mail: Didier.Raoult{at}medecine.univ.mrs.fr.
Infection and Immunity, March 2001, p. 1876-1879, Vol. 69, No. 3
0019-9567/01/$04.00+0 DOI: 10.1128/IAI.69.3.1876-1879.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
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