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Infection and Immunity, March 2001, p. 1880-1882, Vol. 69, No. 3
0019-9567/01/$04.00+0   DOI: 10.1128/IAI.69.3.1880-1882.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Passive Antibody to Bartonella henselae Protects against Clinical Disease following Homologous Challenge but Does Not Prevent Bacteremia in Cats

Kathy L. O'Reilly,1,* Katy A. Parr,1 Tracy P. Brown,1 Belinda Tedder-Ferguson,2 and Daniel T. Scholl2

Department of Veterinary Microbiology and Parasitology1 and Department of Epidemiology and Community Health,2 School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803

Received 26 June 2000/Returned for modification 30 August 2000/Accepted 7 December 2000

We challenged cats transfused with anti-Bartonella serum and kittens born to antibody-positive queens with Bartonella henselae to determine the contribution of antibodies to the control of B. henselae in cats. In both experiments, antibody-positive cats were protected from clinical disease but passive antibody to the homologous strain of B. henselae did not prevent bacteremia.

* Corresponding author. Mailing address: Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803. Phone: (225) 346-3307. Fax: (225) 346-5715. E-mail: oreilly{at}mail.vetmed.lsu.edu.

Infection and Immunity, March 2001, p. 1880-1882, Vol. 69, No. 3
0019-9567/01/$04.00+0   DOI: 10.1128/IAI.69.3.1880-1882.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.




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