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Infect Immun. 1973 January; 7(1): 117-118
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Lack of Detectable Circulating Interferon in Mice Protected Against Vaccinia Virus by Induction and Elicitation with Bacterial Systems

^a Veterans Administration Hospital and Philadelphia General Hospital, Department of Community Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104

ABSTRACT

Mice which had been subjected to mycobacterial infection and specific elicitation were bled from the orbital sinus at the time the mice were challenged intravenously with vaccinia virus. Assays of the sera were negative for interferon. Sera of rabbits sensitized with staphylococci and elicited by Staphage Lysate also lacked detectable circulating interferon.

¹ Present address: Division of Laboratories and Research, New York State Department of Health, Albany, N.Y. 12201.

² Present address: 734 Millbrook Lane, Haverford, Pa. 19041.