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Infect Immun. 1973 April; 7(4): 639-641
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Antibody Response to Chlamydia Agents: Lack of Immunoglobulin M Antibodies During the Secondary Immune Response

Abdallah M. Isa

Department of Microbiology and Division of Immunobiology, Meharry Medical College, Nashville, Tennessee 37208

ABSTRACT

Intramuscular inoculation of the monkey with a massive dose of Chlamydia agent particles resulted in the production of high levels of immunoglobulin M antibodies. These antibodies were broadly specific and reacted to high titers with heterologous antigens. Challenge inoculation of the same monkeys with heterologous Chlamydia agent particles resulted in the production of increased levels of immunoglobulin G but not immunoglobulin M antibodies. Some immunological implications of these results are discussed.

Infect Immun. 1973 April; 7(4): 639-641
Copyright © 1973 American Society for Microbiology. All Rights Reserved.





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J. Bacteriol. J. Virol. Eukaryot. Cell
Microbiol. Mol. Biol. Rev. Clin. Vaccine Immunol. All ASM Journals

Copyright © 1973 by the American Society for Microbiology. All rights reserved.