This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Canaday, D. H.
Right arrow Articles by Dubyak, G. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Canaday, D. H.
Right arrow Articles by Dubyak, G. R.

 Previous Article  |  Next Article 

Infection and Immunity, November 2002, p. 6456-6459, Vol. 70, No. 11
0019-9567/02/$04.00+0     DOI: 10.1128/IAI.70.11.6456-6459.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

ATP and Control of Intracellular Growth of Mycobacteria by T Cells

David H. Canaday,1* Reza Beigi,2 Richard F. Silver,1 Clifford V. Harding,3 W. Henry Boom,1 and George R. Dubyak2

Departments of Medicine,1 Pathology, University Hospitals of Cleveland and Case Western Reserve University,3 Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio 441092

Received 19 February 2002/ Returned for modification 24 April 2002/ Extracellular ATP at millimolar concentrations inhibits growth of mycobacteria in human macrophages. Whether T cells can produce sufficient ATP is unknown. CD4+ and CD8+ T cells did not release sufficient ATP through either degranulation or lysis of bystander cells to restrict growth of Mycobacterium bovis BCG in monocytes.

* Corresponding author. Mailing address: Case Western Reserve University, 10900 Euclid Ave., BRB 1010B, Cleveland, OH 44109-4984. Phone: (216) 368-8901. Fax: (216) 368-2034. E-mail: dxc44{at}cwru.edu.

Editor: S. H. E. Kaufmann

Infection and Immunity, November 2002, p. 6456-6459, Vol. 70, No. 11
0019-9567/02/$04.00+0     DOI: 10.1128/IAI.70.11.6456-6459.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Borsellino, G., Kleinewietfeld, M., Di Mitri, D., Sternjak, A., Diamantini, A., Giometto, R., Hopner, S., Centonze, D., Bernardi, G., Dell'Acqua, M. L., Rossini, P. M., Battistini, L., Rotzschke, O., Falk, K. (2007). Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood 110: 1225-1232 [Abstract] [Full Text]  
  • Myers, A. J., Eilertson, B., Fulton, S. A., Flynn, J. L., Canaday, D. H. (2005). The Purinergic P2X7 Receptor Is Not Required for Control of Pulmonary Mycobacterium tuberculosis Infection. Infect. Immun. 73: 3192-3195 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»