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Infection and Immunity, April 2002, p. 2242-2244, Vol. 70, No. 4
0019-9567/02/$04.00+0     DOI: 10.1128/IAI.70.4.2242-2244.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Campylobacter Protein Glycosylation Affects Host Cell Interactions

Christine M. Szymanski,1,{dagger} Donald H. Burr,2 and Patricia Guerry1*

Enteric Diseases Program, Naval Medical Research Center, Silver Spring ,1 Food and Drug Administration, Beltsville, Maryland2

Received 15 October 2001/ Returned for modification 12 December 2001/ Accepted 16 January 2002

Campylobacter jejuni 81-176 pgl mutants impaired in general protein glycosylation showed reduced ability to adhere to and invade INT407 cells and to colonize intestinal tracts of mice.

* Corresponding author. Mailing address: Enteric Diseases Program, Naval Medical Research Center, 503 Robert Grant Ave., Silver Spring, MD 20910-7500. Phone: (301) 319-7662. Fax: (301) 319-7679. E-mail: guerryp{at}nmrc.navy.mil.

Editor: J. T. Barbieri

{dagger} Present address: Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada.

Infection and Immunity, April 2002, p. 2242-2244, Vol. 70, No. 4
0019-9567/02/$04.00+0     DOI: 10.1128/IAI.70.4.2242-2244.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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