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Infection and Immunity, May 2002, p. 2704-2707, Vol. 70, No. 5
0019-9567/02/$04.00+0     DOI: 10.1128/IAI.70.5.2704-2707.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Intimin Facilitates Colonization by Escherichia coli O157:H7 in Adult Ruminants

Department of Veterinary Microbiology and Preventative Medicine,¹ Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011²

Received 15 November 2001/ Returned for modification 3 January 2002/ Accepted 13 February 2002

We compared the magnitude and duration of fecal shedding of wild-type Escherichia coli O157:H7 to that of an isogenic intimin mutant in young adult cattle and sheep. In both ruminant species, wild-type E. coli O157:H7 was shed in greater numbers and for a longer duration than was the intimin mutant.

Editor: J. D. Clements

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