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Infection and Immunity, November 2003, p. 6607-6609, Vol. 71, No. 11
0019-9567/03/$08.00+0 DOI: 10.1128/IAI.71.11.6607-6609.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.
Cystic Fibrosis/Pulmonary Research and Treatment Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7248,1 FAF Medical Academy, Institute of Microbiology, Munich, Germany2
Received 8 May 2003/ Returned for modification 12 June 2003/ Accepted 13 August 2003
The role of the actin-based cytoskeleton in the internalization process of Burkholderia multivorans by well-differentiated human airway epithelia was investigated by immunohistology and confocal microscopy. Our data suggest that an intact actin cytoskeleton is required for biofilm formation but not single cell entry or paracytosis.
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