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Infection and Immunity, December 2003, p. 7219-7222, Vol. 71, No. 12
0019-9567/03/$08.00+0     DOI: 10.1128/IAI.71.12.7219-7222.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Abortive Potency of Chlamydophila abortus in Pregnant Mice Is Not Directly Correlated with Placental and Fetal Colonization Levels

Amel Bouakane, Ilhem Benchaîeb, and Annie Rodolakis*

Unité de Recherche Pathologie Infectieuse et Immunologie, Institut National de la Recherche Agronomique, Centre de Tours-Nouzilly, 37380 Nouzilly, France

Received 8 July 2003/ Returned for modification 23 July 2003/ Accepted 16 August 2003

Abortion, placental and fetal colonization, and levels of gamma interferon were analyzed for four Chlamydophila abortus strains presenting antigenic variations in a mouse model. Expression of virulence of these strains varied and indicated that abortion was not directly related to the number of bacteria in the placenta, and thus, other factors may have an important role in activating the abortion process.

* Corresponding author. Mailing address: Unité de Pathologie Infectieuse et Immunologie, INRA-Centre de Tours, 37380 Nouzilly, France. Phone: 33 2 47 42 78 88. Fax: 33 2 47 42 77 79. E-mail: annie.rodolakis{at}tours.inra.fr.

Editor: J. T. Barbieri

Infection and Immunity, December 2003, p. 7219-7222, Vol. 71, No. 12
0019-9567/03/$08.00+0     DOI: 10.1128/IAI.71.12.7219-7222.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Buendia, A. J., Ortega, N., Caro, M. R., Del Rio, L., Gallego, M. C., Sanchez, J., Navarro, J. A., Cuello, F., Salinas, J. (2009). B Cells Are Essential for Moderating the Inflammatory Response and Controlling Bacterial Multiplication in a Mouse Model of Vaccination against Chlamydophila abortus Infection. Infect. Immun. 77: 4868-4876 [Abstract] [Full Text]  


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